منابع مشابه
Thermostabilized chondroitinase ABC Promotes Neuroprotection after Contusion Spinal Cord Injury
Background: Chondroitinase ABC (cABC), due to its loosening impact on the extracellular matrix scaffold, has been used to enhance regeneration of injured axonal tracts after spinal cord injury (SCI). However, cABC thermal instability at physiological temperature has limited its clinical application. The disaccharide trehalose has been shown to increase the stability of cABC in body temperature....
متن کاملSexual function in a traumatic spinal cord injured population 10-45 years after injury.
OBJECTIVE To examine sexual function at least 10 years after traumatic spinal cord injury. STUDY DESIGN Cross-sectional questionnaire plus retrospective and prospective data from medical files. SUBJECTS A total of 279 individuals with traumatic spinal cord injury. RESULTS For spinal cord injured women: 94% had no problems with impaired vaginal lubrication; 22% had given birth after the in...
متن کاملP 94: The Systemic Inflammation after Spinal Cord Injury
Spinal cord injury (SCI) actuate to complex cellular and molecular interactions within the central nervous system in a heave to repair the initial tissue damage. The pathophysiology of acute spinal cord injury (SCI) involves primary and secondary mechanisms. Neuroinflammation is an important secondary injury process in SCI. The local inflammatory microenvironment within the injured spinal cord ...
متن کاملNatural Polyphenols and Spinal Cord Injury
Polyphenols have been shown to have some of the neuroprotective effects against neurodegenerative diseases. These effects are attributed to a variety of biological activities, including free radical scavenging/antioxidant and anti-inflammatory and anti-apoptotic activities. In this regard, many efforts have been made to study the effects of various well-known dietary polyphenols on spinal cord ...
متن کاملChondroitinase ABC Administration in Locomotion Recovery After Spinal Cord Injury: A Systematic Review and Meta-analysis
Introduction: The present systematic review and meta-analysis aims to conduct a comprehensive and complete search of electronic resources to investigate the role of administrating Chondroitinase ABC (ChABC) in improving complications following Spinal Cord Injuries (SCI). Methods: MEDLINE, Embase, Scopus, and Web of Sciences databases were searched until the end of 2019. Two independent reviewe...
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ژورنال
عنوان ژورنال: Spinal Cord
سال: 1992
ISSN: 1362-4393,1476-5624
DOI: 10.1038/sc.1992.135